The efficacy study of the active ingredients in Milexin MD was conducted in a group of twenty male and female subjects with severe under eyes circles. The method used was image analysis, conducted on photographs taken under standardized conditions.

Frontal photographs were taken at intervals of one week and at the end of the study in order to obtain mean parameters, thus taking into account slight day-to-day variability.

Protocol:

The subjects applied a cream with the active ingredients in Milexin MD under the eyes. Applications were conducted twice daily for 5 weeks. Each subject acted as his/her own control.

The subjects were asked not to party the evening before the photographs were taken and not to wear make-up for the sessions. Voluntary UV or sun exposure sessions were prohibited.

The twenty subjects had an average age of 57 years.

Reduction of dark circles

A 42% reduction of dark circles under the eyes was observed after 5 weeks of treatment with the active ingredients in Milexin MD.
 

Anti-inflamatory efficacy:

Anti-inflamatory activity reduces microvessel vasolidation (the increase in the internal diameter of a blood vessel that results from relaxation of smooth muscle within the wall of the capillary) and decreases the local leakage of red blood cells. This causes an increase in blood flow. The test showed a decrease in inflamation of 22% in the capillary walls was observed.